The trilogy begins at a near future (Pavlov's Colon - 2048) where the raw comingling of religion, capitalism, and human nature has dragged a bungling world down into muffled, choking crisis. Fortunately, a handful of clear-brained individuals from various corners of the globe are brought together, either by luck or by a well-meaning algorithm, to become pivotal actors on the fragmented world stage. Driven by a shared sense of the profound inanity of the universe, they cobble together a way forward that is undeniably less bad than what almost was, and which allows human consciousness to live on to fight another day.